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Cholesterol

We provide MS-based lipid analysis of Cholesterol in a variety of sample types and deliver results in as little as two weeks.
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Details

Sterol Lipids
Lipid Category
Cholesterol Lipids
Lipid Group
Cholesterol
Lipid Class

About the structure and biological function of Chol

Structure. Cholesterol (Chol) belongs to the group of cholesterol lipids within the sterol lipids. Its structure consists of four linked hydrocarbon rings, the steroid structure. A hydrocarbon tail is linked to one end of the steroid, a hydroxyl group linked to the other end.

Function. Cholesterol has a vital function in animals. It is an essential component of cell membranes and lipid rafts. It is a precursor of steroid hormones and other metabolites such as vitamin D or bile acids. Cholesterol also is important for cell signaling, transport processes, and regulation of gene readout, and an abundant constituent of the water permeability barrier in skin and of myelin in the brain. Further, excess cholesterol is linked to cardiovascular disease.

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Chol lipidomics analysis with
Lipotype

Structural detailsclass level
Variants identified 1
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Skin includes:
TAG, DAG, EOdS, EOS, EOP, EOH, NdS, NS, NP, NH, AdS, AS, AP, AH, Chol, CE

2Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, PC O-, PE O-, Cer, SM, Chol, CE

EXAMPLE STRUCTURE
Chol

General molecular structure of cholesterol.

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Chol
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Lipid Navigator

Categories

Fatty Acyls Glycerolipids Phospholipids Sphingolipids Sterol Lipids Prenol Lipids

Groups

Fatty Acids Fatty Esters Fatty Amides Octadecanoids Eicosanoids Docosanoids Glycerol Esters Ester Phospholipids Ether Phospholipids Diphospha­tidyl­glycerols CDP-Glycerols Sphingoid Bases Ceramide Lipids Cerebrosides Diglycosyl­ceramides Phospho­sphingolipids Gangliosides Globosides Sulfoglyco­sphingolipids Cholesterol Lipids Ergosterol Lipids Isoprenoids Quinones

Classes

FFA LiFA SCFA MCFA LCFA SFA UFA WE CAR NAE oxiOME oxiODE Pgd LT TX LX IsoP oxiETrE oxiETE oxiEPE MaR RvD PD oxiDPA oxiDHA TAG DAG MAG PA PC PE PG PI PS LPA LPC LPE LPG LPI LPS BMP PC O- PE O- LPC O- LPE O- CL CDP-DAG Sph dhSph SphP dhSphP GlcSph GalSph Cer CerP dhCer doxCer EOdS EOS EOP EOH NdS NS NP NH AdS AS AP AH HexCer GlcCer GalCer DiHexCer LacCer SM CerPE IPC MIPC M(IP)2C GM1 GM2 GM3 GM4 GD1 GD2 GD3 GT1 GT2 GT3 GQ1 Gb3 Gb4 Sulf Chol CE Erg EE Sqe oxiSqe UQ
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