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Fatty Acids

We provide MS-based lipid analysis of fatty acids in a variety of sample types and deliver results in six or less weeks.
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Details

Fatty Acyls
Lipid Category
Fatty Acids
Lipid Group

About the structure and biological function of Fatty Acids

Structure. Fatty acids belong to the fatty acyls. Their structure consists of a hydrocarbon chain of variable length with a carboxyl group. The hydrocarbon chain of fatty acids may further contain multiple double bonds, it can be branched or linear, and may feature oxygen containing substituents, such as hydroxyl groups or further carboxyl groups.

Function. Fatty acids are present in all living organisms. Fatty acids can be in free form (free fatty acids, FFA) or linked to complex lipids such as phospholipids. They serve as major building blocks of lipids and thus the precise composition of their hydrocarbon chain fundamentally impacts numerous biological processes. In general, fatty acids serve as the main fuel for cellular energy and are an essential element of animal diet.

Linear fatty acids (LiFA) are particularly important as precursors to many further lipids. The balance of saturated fatty acids (SFA) and unsaturated fatty acids (UFA) attached to membrane lipids profoundly impacts biophysical properties of the plasma membrane. Further, many individual fatty acid lipids, for example some medium chain fatty acid species (MCFA), have been discovered to possess signaling functions.

Fatty Acids lipidomics analysis with Lipotype

Covered classes 7
Approach targeted
Method mass spectrometry
Device Agilent 1290 HPLC + 6495 Triplequad
Quantification yes
Delivery time 6 weeks
Lipidomics data pmol & mol%

CORE STRUCTURE
Fatty Acids

General molecular structure of the lipid group fatty acids.

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Fatty Acids
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Lipid Navigator

Categories

Fatty Acyls Glycerolipids Phospholipids Sphingolipids Sterol Lipids Prenol Lipids

Groups

Fatty Acids Fatty Esters Fatty Amides Octadecanoids Eicosanoids Docosanoids Glycerol Esters Ester Phospholipids Ether Phospholipids Diphospha­tidyl­glycerols CDP-Glycerols Sphingoid Bases Ceramide Lipids Cerebrosides Diglycosyl­ceramides Phospho­sphingolipids Gangliosides Globosides Sulfoglyco­sphingolipids Cholesterol Lipids Ergosterol Lipids Isoprenoids Quinones

Classes

FFA LiFA SCFA MCFA LCFA SFA UFA WE CAR NAE oxiOME oxiODE Pgd LT TX LX IsoP oxiETrE oxiETE oxiEPE MaR RvD PD oxiDPA oxiDHA TAG DAG MAG PA PC PE PG PI PS LPA LPC LPE LPG LPI LPS BMP PC O- PE O- LPC O- LPE O- CL CDP-DAG Sph dhSph SphP dhSphP GlcSph GalSph Cer CerP dhCer doxCer EOdS EOS EOP EOH NdS NS NP NH AdS AS AP AH HexCer GlcCer GalCer DiHexCer LacCer SM CerPE IPC MIPC M(IP)2C GM1 GM2 GM3 GM4 GD1 GD2 GD3 GT1 GT2 GT3 GQ1 Gb3 Gb4 Sulf Chol CE Erg EE Sqe oxiSqe UQ
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