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Fatty Acyls

We provide MS-based lipid analysis of fatty acyls in a variety of sample types and deliver results in six or less weeks.

Details

Fatty Acyls
Lipid Category

About the structure and biological function of Fatty Acyls

Structure. Fatty acyls are one of the eight categories of lipids and contain tens of thousands of lipid species. All of these feature a similar molecular structure: they consist of a hydrocarbon chain with a carboxyl group. The carboxyl group can be linked to a diverse range of substituents, the hydrocarbon chain can be equally diverse, containing double bonds, featuring further substituents, be of variable length and branched or linear.

Function. Fatty acyls are common to all living organisms. Depending on the type of organism, the fatty acyl compositions vary greatly. Fatty acids are the most prominent type of fatty acyls. They are major building blocks of complex lipids but also serve as the main fuel for cellular energy, and impact further biological processes. Fatty amides are a diverse group of fatty acyls mostly related to signaling functions.

Fatty esters serve many roles: from storage compounds and signaling to the oxidative metabolism of fatty acids. Octadecanoids, eicosanoids, docosanoids, and further lipid groups are collectively termed oxylipins. They are most-known for their role in pro-inflammatory processes as well as resolution of inflammation, oxidative stress, and the immune system.

Fatty Acyls lipidomics analysis with Lipotype

Covered classes 25
Approach targeted
Method mass spectrometry
Device Agilent 1290 HPLC + 6495 Triplequad
Quantification yes
Delivery time 6 weeks
Lipidomics data pmol & mol%

CORE STRUCTURE
Fatty Acyls

General molecular structure of the lipid category fatty acyls.

ABOUT LIPOTYPE

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    Friedrich Miescher Institute
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