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Phosphatidyl­glycerol

We provide MS-based lipid analysis of PG phospholipids in a variety of sample types and deliver results in as little as two weeks.
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Details

Phospholipids
Lipid Category
Ester Phospholipids
Lipid Group
Phosphatidyl­glycerol
Lipid Class

About the structure and biological function of PG

Structure. Phosphatidylglycerols (PtdGro, GPGro, or PG) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphoglycerol molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. Phosphatidylglycerols are key intermediates in the biosynthesis of many lipids but especially of cardiolipin. They are essential for the development of normal membranes of chloroplasts and mitochondria in higher plants. In bacteria, phosphatidylglycerols are important for optimal functioning of the bacterial machinery and play a role in protein folding and binding. Further, phosphatidylglycerols have a role in the regulation of the innate immune response in the lungs.

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PG lipidomics analysis with
Lipotype

Structural detailssubspecies level
Variants identified > 500
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Basic includes:
TAG, DAG, PA, PC, PE, PG, PI, PS, SM, CE

2Blood Extended includes:
PA, PG, LPA, LPI, LPC O-, LPE O-, HexCer

EXAMPLE STRUCTURE
PG

An example for the molecular structure of phosphatidylglycerol, specifically PG 14:1;0_16:0;0.

EXAMPLE
PG 14:1;0_16:0;0

An example for the molecular structure of phosphatidylglycerol, specifically PG 14:1;0_16:0;0.

Interested in
PG
analysis?

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Lipid Navigator

Categories

Fatty Acyls Glycerolipids Phospholipids Sphingolipids Sterol Lipids Prenol Lipids

Groups

Fatty Acids Fatty Esters Fatty Amides Octadecanoids Eicosanoids Docosanoids Glycerol Esters Ester Phospholipids Ether Phospholipids Diphospha­tidyl­glycerols CDP-Glycerols Sphingoid Bases Ceramide Lipids Cerebrosides Diglycosyl­ceramides Phospho­sphingolipids Gangliosides Globosides Sulfoglyco­sphingolipids Cholesterol Lipids Ergosterol Lipids Isoprenoids Quinones

Classes

FFA LiFA SCFA MCFA LCFA SFA UFA WE CAR NAE oxiOME oxiODE Pgd LT TX LX IsoP oxiETrE oxiETE oxiEPE MaR RvD PD oxiDPA oxiDHA TAG DAG MAG PA PC PE PG PI PS LPA LPC LPE LPG LPI LPS BMP PC O- PE O- LPC O- LPE O- CL CDP-DAG Sph dhSph SphP dhSphP GlcSph GalSph Cer CerP dhCer doxCer EOdS EOS EOP EOH NdS NS NP NH AdS AS AP AH HexCer GlcCer GalCer DiHexCer LacCer SM CerPE IPC MIPC M(IP)2C GM1 GM2 GM3 GM4 GD1 GD2 GD3 GT1 GT2 GT3 GQ1 Gb3 Gb4 Sulf Chol CE Erg EE Sqe oxiSqe UQ
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