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Phosphatidyl­serine

We provide MS-based lipid analysis of PS phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of PS

Structure. Phosphatidyl-serines (PtdSer, GPSer, or PS) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphoserine molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. Phosphatidyl-serines are essential membrane components and contribute to the organization of protein complexes on the cytosolic side of the membrane, thus facilitating signaling activities. They also serve as precursors for lyso-phosphatidylserines, and for phosphatidylethanolamines. They are essential cofactors that bind to and activate many proteins with signaling functions. Further, phosphatidylserines are an important element of the blood coagulation process in platelets, and have a role in regulation of apoptosis, programmed cell death.

PS lipidomics analysis with
Lipotype

Structural detailssubspecies level
Variants identified > 500
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Basic includes:
TAG, DAG, PA, PC, PE, PG, PI, PS, SM, CE

EXAMPLE STRUCTURE
PS

An example for the molecular structure of phosphatidylserine, specifically PS 16:0;0_16:1;0.

EXAMPLE
PS 16:1;0_26:0;0

An example for the molecular structure of phosphatidylserine, specifically PS 16:1;0_26:0;0.

ABOUT LIPOTYPE

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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    Aldeyra Therapeutics
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    Friedrich Miescher Institute
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    KU Leuven
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    DIfE
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    University of Alberta
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    University of Virginia
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    University College London
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