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Lyso-phosphatidyl­glycerol

We provide MS-based lipid analysis of LPG phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of LPG

Structure. Lyso-phosphatidyl-glycerols (LysoPtdGro, LysoPG, or LPG) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphoglycerol molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Little is known about the function of lyso-phosphatidyl-glycerols in animals. Elevated LPG levels have been detected in acute coronary syndrome and they may be linked to cardiovascular diseases. In bacteria, LPGs are the lipid backbone elements of lipopolysaccharides, structural components of the bacterial capsule which are important virulence factors for many pathogens. Further, LPG lipids serve as precursors for phosphatidylglycerols.

LPG lipidomics analysis with
Lipotype

Structural detailsspecies level
Variants identified > 25
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Extended includes:
LPA, LPC, LPE, LPG, LPI, LPS, PC O-, PE O-, LPC O-, LPE O-, CL, Cer, HexCer

EXAMPLE STRUCTURE
LPG

An example for the molecular structure of lyso-phosphatidylglycerol, specifically LPG 20:2;0.

EXAMPLE
LPG 20:2;0

An example for the molecular structure of lyso-phosphatidylglycerol, specifically LPG 20:2;0.

ABOUT LIPOTYPE

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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    Friedrich Miescher Institute
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