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Ester Phospholipids

We provide MS-based lipid analysis of ester phospholipids in a variety of sample types and deliver results in as little as two weeks.


Lipid Category

About the structure and biological function of Ester Phospholipids

Structure. Ester phospholipids belong to the phospholipids. Their structure consists of a glycerol backbone linked to a phosphorylated “head” group: simply phosphate, phosphorylcholine, phosphorylethanolamine, phosphorylinositol, or phosphorylserine. Ester phospholipids further contain up to two ester-linked fatty acids.

Function. Ester phospholipids are present in all living organisms and participate in innumerous cellular events. They are the major structural component of all biological membranes, from plasma membranes to organellar membranes. The ester phospholipid composition influences their biophysical properties. Further, they are essential to regulating cellular functions directly and indirectly.

The head group of ester phospholipids greatly impacts biological function. Phosphatidates (PA) are key intermediates in the synthesis of all phospholipids. Phosphatidylcholines (PC) play an important role in the transport of lipids in blood. Phosphatidylethanolamines (PE) and phosphatidylglycerols (PG) are vital for mitochondria, and phosphatidylserines (PS) and phosphatidylinositols (PI) are crucial to cell signaling.

Ester Phospholipids lipidomics analysis with Lipotype

Covered classes 13
Approach untargeted/targeted
Method mass spectrometry
Device Q Exactive Orbitrap (280.000 Res)
Agilent 1290 HPLC + 6495 Triplequad
Quantification yes
Delivery time 2-6 weeks
Lipidomics data pmol & mol%

Ester Phospholipids

General molecular structure of the lipid group ester phospholipids.


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    Friedrich Miescher Institute
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    University College London
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