Home   Fatty Acyls   Eicosanoids   PG 

Prostaglandin

We provide MS-based lipid analysis of Pgd fatty acyls in a variety of sample types and deliver results in six or less weeks.

Details

Fatty Acyls
Lipid Category
Eicosanoids
Lipid Group
Prostaglandin
Lipid Class

About the structure and biological function of Pgd

Structure. Prostaglandins (Pgd) belong to the group of eicosanoids within the fatty acyls. Their structure is based on eicosanoic acid, a twenty carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains one five-membered ring made of the carbon atoms eight to twelve. The substituents of the ring define the name of the Pgd species and all prostaglandins contain at least a hydroxyl group on carbon atom 15 and a double bond at carbon atom 13.

Function. Prostaglandins are associated with hormone-like functions. They interact with G-protein-linked receptors on the cell surface to activate cellular signal transduction pathways. Pgds coordinate a multitude of physiological processes, sometimes opposing depending on cell type and stimuli. The best-known function of Pgds in cells is that they modify inflammatory response. Prostaglandin synthesis is inhibited by non-steroidal anti-inflammatory drugs like aspirin to limit their pro-inflammatory effects.

Pgd lipidomics analysis with
Lipotype

Structural detailsmolecular species
Variants identified > 25
Approachtargeted
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Quantificationyes
Delivery time6 weeks
Lipidomics datapmol & mol%
Figuresincluded

ABOUT LIPOTYPE

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

  • Thank you once again. The timing is extremely helpful to us.

    Susan Macdonald

    Aldeyra Therapeutics
  • Thank you very much. The results look fantastic!

    Stan Neufeld

    Friedrich Miescher Institute
  • The high-speed turn around when under revision really helped us!

    Rose E Goodchild

    KU Leuven
  • We highly appreciate the personal support and consultation.

    Rainer Voegeli

    DSM Skin Biology
  • We have been quite impressed. The results clearly indicate a difference.

    Pietro De Camilli

    Yale University
  • Cooperating with Lipotype, I enjoy custom packages and great support!

    Olga Ramich

    DIfE
  • After moving from one continent to another, I still prefer Lipotype!

    Julie Jacquemyn

    University of Alberta
  • Thank you very much for my new and shiny lipidomics data set!

    Ilya Levental

    University of Virginia
  • Lipotype Lipidomics is instrumental to our studies of membranes.

    Christopher J Stefan

    University College London
  • Lipotype is truly dedicated to supporting scientists in their research.

    Anonymous

    Anonymous

Request Analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!