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Oxidized Eicosa­pentaenoic Acid

We provide MS-based lipid analysis of oxiEPE fatty acyls in a variety of sample types and deliver results in six or less weeks.

Details

Fatty Acyls
Lipid Category
Eicosanoids
Lipid Group

About the structure and biological function of oxiEPE

Structure. Oxidized eicosapentaenoic acids (oxiEPE) belong to the group of eicosanoids within the fatty acyls. Their structure is based on eicosanoic acid, a twenty carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains five double bonds, from which their name derives. OxiEPE may further encompass multiple hydroxy groups as well as other oxygen containing substituents.

Function. The biological role of oxidized eicosapentaenoic acids is mainly associated with countering some of the diverse biological functions of eicosatetraenoic acids through inhibiting their biosynthesis. But oxiEPEs also modify the immune system, impact sugar metabolism, and inflammation. Oxidized eicosapentaenoic acids are biosynthetic intermediates to a variety of other eicosanoid lipids and docosanoids. Further, oxiEPE lipids may be responsible for some of the beneficial effects linked to dietary omega-3 fatty acids.

oxiEPE lipidomics analysis with
Lipotype

Structural detailsmolecular species
Variants identified > 10
Approachtargeted
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Quantificationyes
Delivery time6 weeks
Lipidomics datapmol & mol%
Figuresincluded

EXAMPLE STRUCTURE
oxiEPE

An example for the molecular structure of 5-HpEPE.

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