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Diacylglycerol

We provide MS-based lipid analysis of DAG glycerolipids in a variety of sample types and deliver results in as little as two weeks.

Details

Glycerolipids
Lipid Category
Glycerol Esters
Lipid Group
Diacylglycerol
Lipid Class

About the structure and biological function of DAG

Structure. Diacylglycerols (diglycerides, DAG, or DG) belong to the group of glycerol esters within the glycerolipids. Their structure consists of a glycerol backbone linked to two fatty acids. The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. Diacylglycerols have different biological functions, of which many depend on the position of the two fatty acids at the glycerol backbone. Thus, diacylglycerols serve as key intermediates in the synthesis of phospholipids and glycerolipids such as triacylglycerols. They can also function in cellular signaling, and their physical properties influence cell membrane biophysics. They are important immunomodulators. Further, diacylglycerols accumulate in many organs in obesity and can be an important factor in cancer.

DAG lipidomics analysis with
Lipotype

Structural detailssubspecies level
Variants identified > 500
Approachuntargeted
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, PC O-, PE O-, Cer, SM, Chol, CE

2Cells Basic includes:
TAG, DAG, PA, PC, PE, PG, PI, PS, SM, CE

3Skin includes:
TAG, DAG, EOdS, EOS, EOP, EOH, NdS, NS, NP, NH, AdS, AS, AP, AH, Chol, CE

EXAMPLE STRUCTURE
DAG

An example for the molecular structure of diacylglycerol, specifically DAG 18:0;0_20:5;0.

EXAMPLE
DAG 18:0;0_20:5;0

An example for the molecular structure of diacylglycerol, specifically DAG 18:0;0_20:5;0.

ABOUT LIPOTYPE

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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    Aldeyra Therapeutics
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    Friedrich Miescher Institute
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    KU Leuven
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    DSM Skin Biology
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    Yale University
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    DIfE
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    University of Alberta
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    University of Virginia
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    University College London
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